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Ect1/E6E7人宫颈永生化鳞状细胞
Guligeina Abudourexiti, et al. J Gynecol Oncol. 2025 Jun 23;36(6):e127. PMID: 40613114
UPF1 inhibits cervical cancer cell migration and invasion by regulating nonsense-mediated decay of BMP6 and lncRNA WAKMAR2
HIEC-6正常人肠上皮细胞
NCM460人正常肠上皮细胞
Yameng Wang, et al. Nat Commun. 2025 Dec 30;17:1123.
Capsaicin diet drives gut inflammation and exosomal miR-17-3p elevation in idiopathic short stature
TU177人喉鳞癌细胞
HN6人舌鳞癌细胞
Chunhui Tian, et al. Oncol Res. 2026 Apr 22;34(5):34. PMID: 42065048
SLC16A1 Activates the STAT3/SLC7A11 Pathway to Mediate Ferroptosis Resistance and Tumor Progression in Head and Neck Squamous Cell Carcinoma
NOK人正常鳞状上皮细胞
Tingchen Mou, et al. Transl Cancer Res. 2026 Feb 13;15(2):108. PMID: 41815119
COL10A1 transcriptional regulation of ANXA5-mediated ferroptosis is involved in malignant progression of head and neck squamous cell carcinoma
HMC3人小胶质细胞
Di Cui, et al. Mol Pain. 2025 Aug 18;21:17448069251374281. PMID: 40823889
CB2 receptor agonist AM1241 regulating the polarization of microglia reduces morphine tolerance through IL-4/STAT6 pathway
AR42J 大鼠胰腺外分泌细胞
HPDE6-C7 人正常胰腺导管上皮细胞
Qilin Zhu, et al. Hereditas. 2026 Mar 11;163:52. PMID: 41808231
Investigating the role of lncRNA SNHG14 in early diagnosis and prognosis of acute pancreatitis: a bioinformatics exploration
hUC-MSC人脐带间充质干细胞
BV2 小鼠小胶质细胞
Zhipeng Pan, et al. Sci Rep. 2025 Sep 1;15:32226. PMID: 40890196
Umbilical cord-derived exosomes alleviate spinal cord injury by regulating microglial polarization through miR-340-5p-mediated modulation of the JAK/STAT3 signaling pathway
HUVEC人脐静脉血管内皮细胞
Jingyao Yan, et al. Cartilage. 2025 Dec 9:19476035251393382. PMID: 41367171
The Role of THBS-3 in the Regulation of Cartilage Angiogenesis and Fibrosis Via the TGF-β/Smad2/3 Pathway in Osteoarthritis
HUVEC人脐静脉血管内皮细胞
RMC-1大鼠视网膜Muller细胞
Pan Liu, et al. Aging Cell. 2025 May 15;24(8):e70097. PMID: 40374315
Single‐Cell RNA‐Seq Reveals Aging‐Related Impairment of Microglial Efferocytosis Contributing to Apoptotic Cells Accumulation After Retinal Injury
HUVEC人脐静脉血管内皮细胞
Dan Tang, et al. World J Diabetes. 2025 Jun 15;16(6):105173. PMID: 40548267
Mechanism of the epidermal growth factor receptor in promoting endothelial cell dysfunction in gestational diabetes mellitus
HMSC人骨髓间充质干细胞
Kaiyuan Cheng, et al. Clin Interv Aging. 2025 Nov 18;20:2079–2089. PMID: 41282376
MicroRNA-874-3p is a Potential Contributor to Primary Hyperparathyroidism-Induced Osteoporosis
NHA人星形胶质细胞
Shiyuan Zhang, et al. Sci Rep. 2025 Nov 12;15:39666. PMID: 41225028
Circular RNA circNRIP1 promotes glioma progression by regulating the miR-106a-5p/GPR133 pathway
L78人肺腺鳞癌细胞
A549人非小细胞肺癌细胞
Yang Liao, et al. Front Oncol. 2025 Nov 13;15:1609215. PMID: 41323393
Circ_0060927 regulates miR-331-3p/ERK/MAPK pathway reaction in non-small cell lung cancer through METTL14-driven methylation
HSC-2人口底癌细胞
HOEC人口腔上皮细胞
Zhe Zhang, et al. Int J Biol Sci. 2026 Feb 26;22(6):3013–3031. PMID: 41943828
HMGA1 Activates FGFBP1 Transcription to Enhance Angiogenesis Induction and Tumor Progression via FGF2/FGFR1 Pathway
CMT167小鼠肺癌细胞
Xin-yang Li, et al. JCI Insight. 2026 Jan 8;11(4):e190531. PMID: 41505202
IL-21 enhances the cytotoxicity of intratumoral CD8+ T cells, improving radiation efficacy
HLEC人淋巴内皮细胞
Meng Xia, et al. Cell Death Discov. 2025 Oct 27;11:488. PMID: 41145436
CREB5 promotes nodal metastasis of cervical cancer by regulation of APLN-induced lymphangiogenesis
JS1小鼠肝星形细胞
HSC小鼠肝星状细胞
Sijia Huang, et al. PeerJ. 2025 Oct 1;13:e20123. PMID: 41048399
Establishment and evaluation of a circAdpgk-0001 knockdown method using CRISPR–Cas13d RNA-targeting technology
RA-FLSs 类风湿关节炎成纤维样滑膜细胞
MH7A关节炎成纤维细胞
Xiaomeng Luo, et al. J Orthop Translat. 2026 Jan 2;56:101005. PMID: 41836582
CMTM6 promotes synovial proliferation and macrophage polarization by preventing ubiquitination of TAK1 in rheumatoid arthritis
HFLS人滑膜成纤维细胞
HFLS-OA 人滑膜关节炎成纤维细胞
Xinjian Zhang, et al. Arthritis Res Ther. 2025 Dec 18;28:16. PMID: 41413572
RNF152-mediated, ubiquitin-dependent degradation of HSP27 activates the PI3K/AKT pathway, driving synovial inflammatory cascades in TMJOA
HUVEC人脐静脉血管内皮细胞
Di Zhang, et al. Adv Sci (Weinh). 2025 Sep 8;12(44):e07894. PMID: 40919680
Microglia Drive Peripapillary Vascular Density Reduction in Normal Tension Glaucoma by Regulating the Rpl17/Stat5b/Apoa1 Axis
NGEC人正常胃黏膜上皮细胞
HIEC 正常人小肠上皮细胞
Zhenmei Song, et al. J Lipid Res. 2025 Aug 12;66(9):100876. PMID: 40812725
DHA and EPA exacerbate hypoxia-induced ferroptosis in gastric and small intestinal mucosa by disrupting the balance between SLC7A11 upregulation and PUFA-PL accumulation
Dezhi Wang, et al. MedComm (2020). 2026 Apr 9;7(4):e70722. PMID: 41969632
Ipriflavone From Aquilaria malaccensis Lam. Exosome‐Like Nanoparticles Targets Prolyl Hydroxylase Domain Protein 2 (PHD2) to Enhance Hypoxia‐Inducible Factor‐α (HIF‐α) Hydroxylation Thereby Alleviating Hypoxia‐Induced Gastrointestinal Mucosal Ferroptosis
MPAEC小鼠肺动脉内皮细胞
Xu Wang, et al. Cell Mol Biol Lett. 2025 Dec 5;31:4. PMID: 41351040
tsRNA-3040b accumulates R-loop to regulate Trim35 transcription, which leads to disordered glycolysis and promotes PAECs proliferation
HPDE6-C7 人正常胰腺导管上皮细胞
Xihui Ding, et al. Cancer Med. 2025 Aug 28;14(17):e71179. PMID: 40874680
MCPIP1 Controls Hybrid EMT and Tumor Stemness via the IL6/JAK2/STAT3 Axis in Pancreatic Cancer
NHEK正常人表皮角质形成细胞
Liu Tang, et al. Food Sci Nutr. 2025 Nov 23;13(11):e71248. PMID: 41293645
Epigallocatechin‐3‐Gallate Mitigates Atopic Dermatitis‐Like Skin Lesions and Psychiatric Comorbidities by Reducing Oxidative Stress
HAVSMC人主动脉血管平滑肌细胞
Wen Zhao, et al. Foods. 2025 Oct 8;14(19):3441. PMID: 41097609
Modulation of Intestinal Smooth Muscle Cell Function by BL-99 Postbiotics in Functional Constipation
HIBEpiC人肝内胆管上皮细胞
Yongqing Zhao , et al. Cancer Cell Int. 2025 Oct 9;25:345. PMID: 41068957
The role of GPD2 and glycolysis-related genes in cholangiocarcinoma: insights into prognostic biomarkers and tumor-immune interactions
HPASMC人肺动脉平滑肌细胞
Feng Xie , et al. Mediators Inflamm. 2026 Feb 23;2026:5524066. PMID: 41737847
Targeting Pulmonary Hypertension: Elucidating Sophocarpine’s Protective Role via Preclinical Models
HPAEpiC人肺泡上皮细胞
Ting-Ting Chen, et al. Cell Death Dis. 2026 Mar 19;17(1):321. PMID: 41851080
K48 and K63 linkage-competed ubiquitination of BECN1 promotes circPDE4D-mediated autophagy in chronic obstructive pulmonary disease
CA9-22 人口腔上皮癌细胞
Yuan Ping, et al. Front Immunol. 2026 Feb 26;17:1744612. PMID: 41836404
NOX2 exacerbates periodontitis via JAK2-STAT3-mediated ferroptosis of gingival epithelial cells
Hacat 人永生化角质形成细胞
Yushan Zhang, et al. Adv Sci (Weinh). 2025 Nov 20;13(7):e10164. PMID: 41267387
Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis
T98G 人脑胶质细胞瘤
Xuejun Cao, et al. Cell Oncol (Dordr). 2026 Jan 8;49(1):21. PMID: 41505038
Targeting VCP with V8 suppresses glioblastoma development via formation of aggregates and disruption of mitophagy flux
HCC-1588人肺鳞癌细胞
PC-10人肺鳞癌细胞
Feng Shi, et al. Respir Res. 2025 Sep 29;26:275. PMID: 41024125
ZNF184-mediated transcriptional activation of SAE1 drives the cell cycle entry and immune evasion in non-small cell lung cancer
293T人胚肾细胞
SJSA-1人骨肉瘤细胞
MNNG/HOS Cl #5 [R-1059-D]人骨肉瘤细胞
U2OS人骨肉瘤细胞
Chaotao Chen, et al. Mol Cancer. 2026 Jan 19;25:49. PMID: 41549277
METTL3-mediated m6A modification of CACNA1E promotes osteosarcoma progression and chemoresistance by enhancing WNT7B-mediated Ca2+ signaling
HOK人正常口腔角质细胞
Xie Li, et al. Front Immunol. 2026 Apr 14;17:1789261. PMID: 42058186
Hypoxia inducible factor 1 subunit alpha mediates autophagy disorder of oral lichen planus by regulating lysosomal pathway
DC2.4小鼠骨髓来源树突状细胞
Jindong Zhang, et al. BMC Biotechnol. 2026 Feb 28;26:39. PMID: 41764485
Nanoparticles co-loaded with bacillus Calmette-Guérin pure protein derivative and doxorubicin for bladder tumor therapy
GMI-R1大鼠小胶质细胞
Xiongjie Xu , et al. J Inflamm Res. 2026 Mar 16;19:574990. PMID: 41867458
Integrated Multi-Omics Analysis Reveals IRF1-Driven Microglial PANoptosis via ZBP1 in Spinal Cord Injury
Yang Tan, et al. Mediators Inflamm. 2026 Jan 22;2026:5595023. PMID: 41583121
After Traumatic Brain Injury, EPHA4 Enhances Endoplasmic Reticulum Stress to Promote M1 Microglial Polarization Through the MAPK Signaling Pathway
HRVEC人视网膜微血管内皮细胞
Xuemin He, et al. Mol Ther Nucleic Acids. 2026 Jan 24;37(1):102847. PMID: 41717290
An atlas of cGAS-STING signaling in pathophysiological angiogenesis and retinal vascular homeostasis across species
SCC-15 人舌磷癌细胞
HOEC人口腔上皮细胞
Lina Yang, et al. Exp Biol Med (Maywood). 2025 Sep 19;250:10623. PMID: 41049606
Prognostic significance and therapeutic implications of redox metabolism-related genes in head and neck squamous cell carcinoma
LNCAP人前列腺癌细胞
Jianhui Li, et al. PLoS One. 2026 Jan 29;21(1):e0341064. PMID: 41610125
Effects of silybin on triptorelin-induced bone metabolic abnormalities in prostate cancer revealed based on TMT-based proteomics
SVOG人卵巢颗粒细胞
KGN 人卵巢颗粒细胞
Shenghui Zhang, et al. J Ovarian Res. 2025 Dec 22;18:305. PMID: 41430290
Mesenchymal stem cells derived extracellular vesicles ameliorate ovarian aging through inhibiting LGALS3BP/NF-κB induced inflammation
293T人胚肾细胞
Jiayuanyuan Fu, et al. Sci Adv. 2025 Nov 26;11(48):eadz1243. PMID: 41296848
Brain-derived extracellular vesicles circUsp32 polarized macrophages causing acute kidney injury after traumatic brain injury
HFLS-RA 类风湿关节炎成纤维样滑膜细胞
Zhibin Zhang, et al. Front Med (Lausanne). 2026 Apr 13;13:1803764. PMID: 42051728
Identification of diagnostic genes in rheumatoid arthritis using integrated bioinformatics, machine learning, and experimental validation
RPDLSC细胞
Hao Jin, et al. Nat Commun. 2025 Nov 18;16:10075. PMID: 41253826
Cu/Zn/histidine supramolecular assemblies with optimized Cu catalytic sites as an alternative of superoxide dismutase
C4-2 人前列腺癌细胞
C4-2B 人前列腺癌细胞
Jia-Yin Chen, et al. Cell Death Dis. 2026 Mar 19;17(1):282. PMID: 41856970
A feedback mechanism from prostate cancer cells to macrophages, reinforced by STAT1, regulates tumor progression and resistance to radiotherapy
HCMEC(BL12-H) 人结肠微血管内皮细胞
HPMEC人肺微血管内皮细胞
Shuren Wang, et al. Nat Commun. 2026 Feb 14;17:2778. PMID: 41690961
Amelioration of colorectal cancer-associated fibroblasts in immunosuppressive microenvironment by ferroptosis-based nanotherapy
ROS17/2.8大鼠成骨细胞
Tong Li, et al. J Transl Med. 2026 Feb 6;24:335. PMID: 41652636
Luteolin ameliorates steroid-induced osteonecrosis of the femoral head via a gut microbiota–L-Carnitine–IFIH1 axis
MN9D 小鼠中脑多巴胺能神经元细胞
Zixin Tan, et al. Acta Neuropathol Commun. 2025 Nov 4;13:223. PMID: 41189023
Transaldolase 1 impacts Parkinson’s disease pathogenesis via metabolic reprogramming and autophagy-lysosomal pathway
MODE-K 小鼠小肠上皮细胞系
Xianggui Yin, et al. Nat Commun. 2025 Oct 17;16:9229. PMID: 41107261
Efficient active hydrogen delivery for drug-free radiation enteritis therapy in mice
BeWo 人胎盘绒毛癌-细胞
Yetian Zhao, et al. Virol J. 2025 Nov 17;22:379. PMID: 41250199
Influenza a(H1N1) virus infection impairs syncytiotrophoblast functions by promoting ferroptosis through the TNF-α/ISG15/EGR1 axis
A2780人卵巢癌-细胞
ID8小鼠卵巢癌-细胞
Mengna Shi, et al. Mater Today Bio. 2025 Sep 14;35:102307. PMID: 41080722
A novel folate receptor-targeted curcumin nano-delivery system: A dual therapeutic strategy for precise inhibition of MRCKβ to suppress ovarian cancer proliferation and immune escape
MB49小鼠膀胱癌-细胞
Yadong Liui, et al. Int J Nanomedicine. 2026 Apr 11;21:587614. PMID: 41993779
Microwave-Responsive MnFe-Based Molybdenum Disulfide Nanoflowers for Enhanced Thermal-Dynamic-Chemo Synergistic Therapy in Bladder Cancer
HOEC人口腔上皮细胞
HUVEC人脐静脉血管内皮细胞
Xiaomeng Wang, et al. J Nanobiotechnology. 2026 Feb 16;24:259. PMID: 41699655
Polyphenolic nanodot-integrated spindle nanoplatform heals oral mucositis via microbiota restoration and glycolysis inhibition
mEC25小鼠食管鳞癌-细胞
Lihua Wang, et al. Cell Biol Toxicol. 2025 Nov 12;41(1):150. PMID: 41219497
CBX6 induces CD8+ T cell exhaustion and tumor development in esophageal squamous cell carcinoma through SMARCD1-mediated CCL8 secretion and lactate efflux
SW 1353人软骨肉瘤细胞
Rui Yan, et al. Bioact Mater. 2025 Oct 29;56:483–508. PMID: 41234294
Injectable microgels loaded with programmable WELNs based on mendelian randomization macroanalysis alleviate osteoarthritis by restoring the circadian rhythm
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