深圳市豪地华拓生物科技有限公司

目录多肽系列

Calcineurin Autoinhibitory Peptide

产品名称 : Calcineurin Autoinhibitory Peptide

产品类别 : 目录多肽
品  牌 : ABBIOTEC
货  号 : 350004
规  格 : 1 mg
详细信息
序  列 : Ile-Thr-Ser-Phe-Glu-Glu-Ala-Lys-Gly-Leu-Asp-Arg-Ile-Asn-Glu-Arg-Met-Pro-Pro-Arg-Arg-Asp-Ala-Met-Pro or ITSFEEAKGLDRINERMPPRRDAMP
分  子  量 : 2930.4 g/mol
纯  度 :Purity > 95% by HPLC
形  态 :Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.
溶  解: Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
保存条件 :Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
别  名 :Serine/Threonine-protein phosphatase 2B catalytic subunit alpha isoform; Calmodulin-dependent calcineurin A subunit alpha isoform; CAM-PRP catalytic subunit; PPP3CA; CALNA; CAN
产品描述 :This peptide is a specific inhibitor for calcineurin (PP2BA), a Ser/Thr protein phosphatase from the PPP family and PP2B subfamily. The peptide corresponds to the residues 467-491 within the inhibitory domain of human calcineurin alpha subunit. Calcineurin is known to dephosphorylate heat shock protein beta-1 (HSPB1) and protein phosphatase Slingshot homolog 1 (SSH1). This peptide inhibits Mn2+-stimulated calcineurin activity (IC50 = 10 uM using 32P-myosin light chain as substrate) but has no effect on Ni2+-stimulated enzyme activity. It does not inhibit CaMKII kinase, protein phosphatase 1 or 2A.
产品链接 http://www.ABBIOTEC.com/peptides/Calcineurin-Autoinhibitory-Peptide
 
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