PTTG1 Antibody_华拓生物

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PTTG1 Antibody

产品名称 ： PTTG1 Antibody

中文名称 ：乳头瘤病毒调控因子1抗体

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0402961

规　　格 ： 0.1mg(1mg/ml)

详细信息

克隆类型：	Rabbit Polyclonal IgG
免疫原：	peptide corresponding to a sequence at the C-terminus of human Securin.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	Securin, also known as pituitary tumor-transforming 1 or EAP1 is a protein that in humans is encoded by the PTTG1 gene. PTTG1 gene is mapped to 5q33.3. The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex(APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box(D box) that is required for its degradation by the APC.
适用物种：	Hu
应用说明：	WB: 1:200-1:1000
别　　名：	Securin;Esp1-associated protein;Pituitary tumor-transforming gene 1 protein;Tumor-transforming protein 1;hPTTG;PTTG1;EAP1, PTTG, TUTR1.
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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