Cdc6 Antibody_华拓生物

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Cdc6 Antibody

产品名称 ： Cdc6 Antibody

中文名称 ：细胞分裂周期蛋白6抗体

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0401219

规　　格 ： 0.1mg(1mg/ml)

详细信息

克隆类型：	Mouse IgG1
免疫原：	Recombinant human Cdc6.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	n yeasts, Cdc6(Saccharomyces cerevisiae) and Cdc18(Schizosaccharomyces pombe) associate with the origin recognition complex(ORC) proteins to render cells competent for DNA replication. Cdc6 is overexpressed in human cancers, where it has a critical regulatory role in addition to DNA replication. Yan et al.(1998) showed that Cdc6 is expressed selectively in proliferating but not quiescent mammalian cells, both in culture and within tissues in intact animals. During the transition from a growth-arrested to a proliferative state, transcription of mammalian Cdc6 is regulated by E2F proteins, as revealed by a functional analysis of the human Cdc6 promoter and by the ability of exogenously expressed E2F proteins to stimulate the endogenous Cdc6 gene.
适用物种：	Hu
应用说明：	WB: 1:100-1:500
别　　名：	CDC18L;HsCdc18;p62(cdc6);CELL DIVISION CYCLE 18, S. POMBE, HOMOLOG-LIKE;CDC6(cell division cycle 6, S. cerevisiae) homolog;CELL CYCLE CONTROLLER CDC6;CDC6-related protein;Cdc18-related protein.
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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