| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
Mouse IgG2a |
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免 疫 原 ： |
Membrane extract of detergent-lysed erythrocytes |
|
产品描述 ： |
This antibody recognizes the C5b-9 complement components, also named the terminal complement complex (TCC) that consists of the C5b, C6, C7, C8 and C9 components. The antibody specifically binds to a neoepitope exposed on C9 component upon complex formation in both membrane-bound (MAC) and fluid phase (SC5b-9) complexes. The antibody can be used for detecting C5b-9 in ELISA and immunohistocytology. The neoepitope is destroyed upon complex disruption during a western blot procedure. |
| 适用物种 ： |
H, P, Hs, Mk |
|
应用范围 ： |
E, IHC, IF |
| 应用说明 ： |
This antibody recognizes human C5b-9, also called the terminal complement complex (TCC) made of C5b, C6, C7, C8 and C9. The antibody is directed against a neoepitope exposed in C9 upon TCC complex formation. The antibody does not work in WB but is suitable for IHC with frozen and paraffin sections. The antibody also reacts with porcine and equine TCC. |
| 别 名 ： |
Terminal complement complex; TCC; C5b; C6; C7; C8; C9; Complement component |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
Mollnes, TE et al. 1985. Scand J Immunol. 22(2): 183-95. PMID# 4035298 |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/c5b-9-complement-antibody |
| 标 记 物 ： |
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产品说明 ： |
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