克隆类型 : |
Mouse Monoclonal Antibody |
亚 型 : |
Mouse IgG1/k |
免 疫 原 : |
C3 isolated from human plasma |
产品描述 : |
C3 is a key component of the complement system since classical and alternative activation pathways merge at the C3 activation step when C3 is split into C3a and C3b. The molecular mass of C3 is 185 kDa and it consists of two chains (110 kDa and 75 kDa) held together by disulfide bonds. This antibody is specific for human C3. |
适用物种 : |
H |
应用范围 : |
E, WB |
应用说明 : |
Product Cat. No. 250289 reacts strongly with C3. Strong reaction is seen in ELISA with C3 directly coated onto the microtiter well, and also when tested in sandwich ELISA in combination with a polyclonal antibody against C3. In Western blot, Product Cat. No. 250289 reacts with C3 in reduced as well as non-reduced forms. E: 1:16,000; WB: 1:1,000 |
别 名 : |
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; Complement C3; C3a anaphylatoxin; Complement C3b alpha chain; Complement C3c alpha chain fragment 1; Complement C3dg fragment; C3d fragment; C3g fragment; C3f fragment; C3c alpha chain fragment 2 |
形 态 : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
保存条件 : |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
产品文献 : |
Agrahari G et al. 2013. J Biol Chem. 2013. 288(38):27494-27504. PMID# 23928307. Complement-mediated Opsonization of Invasive Group A Streptococcus pyogenes Strain AP52 is Regulated by the Bacterial T |
产品链接 : |
http://www.abbiotec.com/antibodies/c3-complement-2d8-antibody |
标 记 物 : |
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产品说明 : |
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