| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
Mouse IgG1/k |
|
免 疫 原 ： |
Complemen factor B purified from human plasma and adsorbed to aluminum hydroxide gel |
|
产品描述 ： |
Factor B is a component of the alternative pathway of complement activation. The protein consists of a single polypeptide chain of molecular mass 93 kDa, and has a concentration in plasma of approximately 200 ,mg/mL. Factor B is cleaved by factor D into the Ba component (30 kDa) and the Bb (63 kDa). Together with C3b, Bb forms the alternative pathway C3 convertase C3bBb. This antibody is specific for the Bb fragment of human factor B. Antibody binding abolishes the formation of C3bBb complexes. |
| 适用物种 ： |
H |
|
应用范围 ： |
E, WB |
| 应用说明 ： |
Product Cat. No. 250291 reacts strongly with human factor B. Strong reaction is seen when used as detection antibody in sandwich ELISA with a polyclonal capture antibody against factor B. In Western blot, Product Cat. No. 250291 reacts with the Bb fragment of factor B in its non-reduced form only. Product Cat. No. 250291 can be used for the affinity purification of human factor B when coupled to a suitable matrix. E: 1:13,000; WB: 1:1,000 |
| 别 名 ： |
C3/C5 convertase; Properdin factor B; Glycine-rich beta glycoprotein; GBG; PBF2 |
|
形 态 ： |
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件 ： |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/factor-b-9b8-antibody |
| 标 记 物 ： |
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产品说明 ： |
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