| 克隆类型 ： |
Mouse Monoclonal Antibody |
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亚 型 ： |
Mouse IgG1/k |
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免 疫 原 ： |
Diphtheria toxoid prepared from toxin purified from C. diphtheriae subsp. intermedius Park-Williams no. 8 by formaldehyde inactivation (2), and adsorbed to aluminum hydrtoxide gel. |
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产品描述 ： |
Corynebacterium diphtheriae is a Gram-positive, non-motile bacterium that can cause serious illness in unvaccinated humans. C. diphtheriae infects the epithelial cells of the upper respiratory tract from where they secrete a potent toxin that is absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body. The toxin is a single protein chain of 62 kDa which is "nicked" at proteolytic processing sites to produce an A chain of 21 kDa and a B chain of 40 kDa, held together by a disulfide bridge. The A-chain carries the ADP-ribosylation enzymatic activity responsible for the toxic action. This antibody reacts with diphtheria toxoid and also neutralizes diphtheria toxin in a VERO cell assay. |
| 适用物种 ： |
Cd, Bact |
|
应用范围 ： |
E |
| 应用说明 ： |
Product Cat. No. 250347 reacts strongly with diphtheria toxoid in sandwich ELISA in combination with a polyclonal antibody against the toxoid as capture antibody. The antibody also reacts in ELISA with diphtheria toxoid coated directly onto the microtiter well. Biotinylated Product Cat. No. 250347 can be used as a detection antibody in a sandwich ELISA with Product Cat. No. 250348 used as a capture antibody. E: 1:35,000 |
| 别 名 ： |
DT; NAD(+)--dipthamide ADP-ribosyltransferase |
|
形 态 ： |
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件 ： |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/corynebacterium-diphtheriae-toxoid-176b9-antibody |
| 标 记 物 ： |
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产品说明 ： |
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