| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
Mouse IgG1/k |
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免 疫 原 ： |
Diphtheria toxoid prepared from toxin purified from C. diphtheriae subsp. intermedius Park-Williams no. 8 by formaldehyde inactivation (2), and adsorbed to aluminum hydrtoxide gel |
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产品描述 ： |
Corynebacterium diphtheriae is a Gram-positive, non-motile bacterium that can cause serious illness in unvaccinated humans. C. diphtheriae infects the epithelial cells of the upper respiratory tract from where they secrete a potent toxin that is absorbed and disseminated through lymph channels and blood to the susceptible tissues of the body. The toxin is a single protein chain of 62 kDa which is "nicked" at proteolytic processing sites to produce an A chain of 21 kDa and a B chain of 40 kDa, held together by a disulfide bridge. The A-chain carries the ADP-ribosylation enzymatic activity responsible for the toxic action. This antibody reacts with diphtheria toxoid. |
| 适用物种 ： |
Cd, Bact |
|
应用范围 ： |
E, WB |
| 应用说明 ： |
Product Cat. No. 250348 reacts in ELISA wells coated with diphtheria toxoid. Product Cat. No. 250348 detects in western blot a band at approximately 63 kDa corresponding to the toxin proenzyme. Biotinylated Product Cat. No. 250347 can be used as a detection antibody in a sandwich ELISA with Product Cat. No. 250348 used as a capture antibody. E: 1:8,000; WB: 1:500 |
| 别 名 ： |
DT; NAD(+)--dipthamide ADP-ribosyltransferase |
|
形 态 ： |
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件 ： |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/corynebacterium-diphtheriae-toxoid-11d9-antibody |
| 标 记 物 ： |
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产品说明 ： |
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