| 克隆类型 ： |
Mouse Monoclonal Antibody |
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亚 型 ： |
Mouse IgG1/k |
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免 疫 原 ： |
MBL purified from human donor plasma and adsorbed onto aluminum hydroxide |
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产品描述 ： |
Mannan-binding lectin (MBL), also called mannose-binding lectin or protein, belongs to the C-type family of collectins, showing calcium-dependent binding to certain sugars. It consists of oligomers of triple-chain subunits and its binding and complement activating activities depend on its normal oligomerization. On binding to mannan-like microbial surface carbohydrates, MBL activates the complement system by means of its own lectin pathway, depending on the MBL-associated serine proteases (MASPs). Because of the presence of different structural and promoter alleles in the population, 12% or more of the population have low concentrations (<50ng/mL) of normally oligomerized, functional MBL in plasma or serum. This antibody is specific for human MBL from plasma or serum, but cross-reacts strongly with MBL from horse and swine. |
| 适用物种 ： |
H, Hs, P |
|
应用范围 ： |
E |
| 应用说明 ： |
Product Cat. No. 250356 reacts strongly with human, horse and swine serum in ELISA when immobilized on mannan-coated microplate. A weaker reaction is seen when Product Cat. No. 250356 is used as a detection antibody for human MBL coated directly onto the microtiter plate. E: 1:250; WB: 1:100 |
| 别 名 ： |
Mannose-binding protein C; MBP-C; MBP1; Mannose-binding lectin; mannan-binding protein; MBL2; MBL |
|
形 态 ： |
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件 ： |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/mannan-binding-lectin-horse-15c5-antibody |
| 标 记 物 ： |
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产品说明 ： |
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