| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
Mouse IgG1/k |
|
免 疫 原 ： |
MBL purified from human donor plasma and adsorbed onto aluminum hydroxide |
|
产品描述 ： |
Mannan-binding lectin (MBL), also called mannose-binding lectin or protein, belongs to the C-type family of collectins, showing calcium-dependent binding to certain sugars. It consists of oligomers of triple-chain subunits and its binding and complement activating activities depend on its normal oligomerization. On binding to mannan-like microbial surface carbohydrates, MBL activates the complement system by means of its own lectin pathway, depending on the MBL-associated serine proteases (MASPs). Because of the presence of different structural and promoter alleles in the population, 12% or more of the population have low concentrations (<50ng/mL) of normally oligomerized, functional MBL in plasma or serum. This antibody is specific for human MBL from plasma or serum, but cross-reacts with MBL from rat. |
| 适用物种 ： |
R |
|
应用范围 ： |
E |
| 应用说明 ： |
Product Cat. No. 250357 reacts with rat serum in ELISA when immobilized on mannan-coated microplate. Product Cat. No. 250357 also reacts with human MBL coated directly onto the microtiter plate. E: 1:2,000; WB: 1:200 |
| 别 名 ： |
Mannose-binding protein C; MBP-C; MBP1; Mannose-binding lectin; mannan-binding protein; MBL2; MBL |
|
形 态 ： |
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件 ： |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/mannan-binding-lectin-rat-11f11-antibody |
| 标 记 物 ： |
|
|
产品说明 ： |
|
