| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Native SP-A purified from bronchioaveolar lavage from proteinosis patients |
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产品描述 ： |
Surfactant protein A (SP-A) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-D and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is 45 ng/ml in healthy individuals. This antibody is specific for human pulmonary SP-A. |
| 适用物种 ： |
H |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
Product Cat. No. 250400 reacts in western blot with reduced forms of SP-A, but weakly with non-reduced forms. Product Cat. No. 250400 reacts specifically with human SP-A in immunohistochemical staining of paraffin-embedded tissue samples. Immunoreactivity is seen in alveolar type II cells, nonciliated bronchial cells and a subset of alveolar macrophages. No reactivity is seen in samples from pancreas, intestines, thymus, prostate gland and peritoneal cavity-lining cells. Product Cat. No. 250400 reacts strongly in ELISA with SP-A directly coated onto the microtiter well. E: 1:16,000; WB: 1:1,000; IHC: 1:3,000 |
| 别 名 ： |
Pulmonary surfactant-associated protein A1; SP-A1; SP-A; PSP-A; PSPA; Alveolar proteinosis protein; 35 kDa pulmonary surfactant-associated protein |
|
形 态 ： |
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件 ： |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
|
产品文献 ： |
Tzouvelekis A et al. 2013. BioMed Research International. ID 654354 |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/surfactant-protein-6f10-antibody |
| 标 记 物 ： |
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产品说明 ： |
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