| 克隆类型 ： |
Rabbit Polyclonal Antibody |
|
亚 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human B7-H4. |
|
产品描述 ： |
Immune costimulatory protein B7-H4 (B7-H4) is expressed on the surface of a variety of immune cells and functions as a negative regulator of T cell response. By arresting cell cycle, B7-H4 inhibits growth, cytokine secretion and cytotoxicity development. When expressed on the cell surface of tumor macrophages, B7-H4 plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. B7-H4 is also involved in promoting epithelial cell transformation. B7-H4 can be a predictive marker for renal cell carcinoma. |
| 适用物种 ： |
H, M, R |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-500 |
| 别 名 ： |
V-set domain-containing T-cell activation inhibitor 1; Immune costimulatory protein B7-H4; B7h.5; T-cell costimulatory molecule B7x; Protein B7S1; VTCN1; B7H4 |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
[1] Zhao X et al. 2016. Oncol Rep. 36(1): 419-27. PMID 27177355. [2] Galazka K et al. 2012. American Journal of Reproductive Immunology. 68(1):85-93. PMID 22530960. [3]Basta P et al. American Journal |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/b7-h4-antibody |
| 标 记 物 ： |
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产品说明 ： |
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