| 克隆类型 ： |
Rabbit Polyclonal Antibody |
|
亚 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse CD68. |
|
产品描述 ： |
The CD68 antigen is involved in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 binds to tissue- and organ-specific lectins and selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane helps macrophages to move over selectin-bearing substrates and other cells. CD68 is highly expressed by blood monocytes and tissue macrophages as well as many tumor cell lines promoting binding to selectins on vascular endothelium facilitating dissemination to secondary sites. |
| 适用物种 ： |
M, R |
|
应用范围 ： |
E, WB, IHC, IF |
| 应用说明 ： |
E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500; IF: 1:100-1:500 |
| 别 名 ： |
Macrosialin; Gp110; CD68 |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
[1] Zalfa C et al. 2016. Cell Death Dis. 7(8): e2311. PMID 27512952. [2] Alcalá M. et al. 2015. Obesity (Silver Spring). 23(8):1598-606. PMID 26148343. [3] Hsieh C-H. et al. 2013. PLOS One. 8(9) e7291 |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/cd68-antibody |
| 标 记 物 ： |
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产品说明 ： |
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