| 克隆类型 ： |
Mouse Monoclonal Antibody |
|
亚 型 ： |
mouse IgG2a |
|
产品描述 ： |
The CD45RA (HI100) antibody recognizes the 205/220-kDa isoform of leukocyte common antigen expressed on 40-50% peripheral CD4+ T cells, 50% peripheral CD8+ T cells and a portion of B cells and monocytes. Studies have shown that expression of different isoforms is characteristic of differentiated subset of hematopoietic cells (for instance CD45RA on naïve/ resting T cells and CD45RD on memory/ activated T cells; CD45RA on medullary thymocytes and CD45RD on cortical thymocytes). It is also reported that the pattern of 87% of B-ALL is CD45RA+/ CD45RO-, 70% of T-ALL is CD45RA-/ CD45RD+ and 78% of B-ALL is CD45RA+/ CD45RO+. |
| 适用物种 ： |
H |
|
应用范围 ： |
E, FC, IHC |
| 应用说明 ： |
Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen and formalin-fixed paraffin sections. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500 |
| 别 名 ： |
Leukocyte common antigen; L-CA; T200; CD45 antigen; PTPRC; Protein tyrosine phosphatase receptor type C |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
产品文献 ： |
[1] Shen DC et al. 1991. J. Monoclonal Antibody. 7(1):53. [2] Knapp W et al. eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. P798, 1078, Oxford University Press, New York. [3] |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/cd45ra-hi100-antibody |
| 标 记 物 ： |
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产品说明 ： |
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