| 克隆类型 ： |
Rabbit Polyclonal Antibody |
|
亚 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD254. |
|
产品描述 ： |
Tumor necrosis factor ligand superfamily member 11 (CD254) is a cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. CD254 augments the ability of dendritic cells to stimulate naive T-cell proliferation. CD254 is an important regulator of interactions between T-cells and dendritic cells and plays a role in the regulation of the T-cell-dependent immune response. CD254 also plays a role in enhanced bone-resorption in humoral hypercalcemia of malignancy. Defects in CD254 are the cause of osteopetrosis autosomal recessive type 2 (OPTB2), also known as osteoclast-poor osteopetrosis. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. |
| 适用物种 ： |
H, M, R, D, P, B |
|
应用范围 ： |
E, WB, IHC |
| 应用说明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 别 名 ： |
RANKL; Osteoprotegerin ligand; OPGL; Tumor necrosis factor ligand superfamily 11; Receptor activator of nuclear factor kappa B ligand; TNF-related activation-induced cytokine; TRANCE; Osteoclast differentiation factor; ODF; CD254 |
|
形 态 ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 产品链接 ： |
http://www.abbiotec.com/antibodies/cd254-antibody |
| 标 记 物 ： |
|
|
产品说明 ： |
|
|
