克隆类型 : |
Rabbit Polyclonal Antibody |
亚 型 : |
Rabbit Ig |
免 疫 原 : |
Human recombinant CYP1A2 |
产品描述 : |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, cytochrome P450 1A2 (CYP1A2) is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. CYP1A2 is most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by CYP1A2 in the liver through an initial N3-demethylation. It also acts in the metabolism of aflatoxin B1 and acetaminophen. CYP1A2 participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. It catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin. |
适用物种 : |
H, M |
应用范围 : |
E, WB, IHC |
应用说明 : |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
别 名 : |
CYP1A2; Cytochrome P450 1A2; CYPIA2; cytochrome P(3)450; P450-P3 |
形 态 : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
保存条件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
产品链接 : |
http://www.abbiotec.com/antibodies/cyp1a2-antibody |
标 记 物 : |
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产品说明 : |
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