克隆类型 : |
Rat Monoclonal Antibody;Clone number:53.6.7 |
亚 型 : |
Rat IgG2a |
纯化方式 : |
Concentration:0.2 mg/ml |
缓 冲 液 : |
PBS pH 7.2, 0.09% NaN3, 0.2% BSA |
产品描述 : |
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck. |
适用物种 : |
Mouse |
应用范围 : |
FC |
应用说明 : |
The amount of the reagent is suggested to be used ≤ 0.25 µg /10^6 cells in 100 µl |
保存条件 : |
Store at 4°C and protected from prolonged exposure to light. Do not freeze. |
标 记 物 : |
PerCP |
产品说明 : |
|
|