克隆类型 : |
Rat Monoclonal Antibody;Clone number:FGK4.5 |
亚 型 : |
Rat IgG2a |
纯化方式 : |
Concentration:0.2 mg/ml |
缓 冲 液 : |
PBS pH 7.2, 0.09% NaN3, 0.2% BSA |
产品描述 : |
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154(gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
适用物种 : |
Mouse |
应用范围 : |
FC |
应用说明 : |
The amount of the reagent is suggested to be used ≤ 1.0 µg/10^6 cells in 100 µl |
保存条件 : |
Store at 4°C and protected from prolonged exposure to light. Do not freeze. |
标 记 物 : |
APC |
产品说明 : |
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