phospho-MEK5(Ser311+Thr315) Antibody

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产品名称 ： phospho-MEK5(Ser311+Thr315) Antibody

中文名称 ：磷酸化丝裂原活化蛋白激酶激酶5抗体

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0304514

规　　格 ： 0.1mg(1mg/ml)

详细信息

克隆类型：	Rabbit Polyclonal IgG
免疫原：	PhosphoPeptide derived from human MEK5 around the phosphorylation site of Ser311+Thr315.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	MEK5 is a dual specificity protein kinase belonging to thr Ser/Thr protein kinase family, (MAP kinase kinase family). It is activated by phosphorylation on Ser/Thr by MAP kinase kinases and interacts specifically with ERK5, and not with another MAP kinase like P38. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). It is not phosphorylated by RAFA, RAFB or RAFC and it may interact with GTPases such as CDC42. The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation.
适用物种：	Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Sheep,
应用说明：	WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500
别　　名：	MAP2K5 (phospho S311/T315); Dual specificity mitogen activated protein kinase kinase 5; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPKK5; PRKMK5; EC 2.7.12.2.
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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