| 克隆类型 : |
Rabbit Polyclonal IgG |
|
免 疫 原 : |
Peptide derived from human TTF-2. |
|
纯化方式 : |
Immunogen affinity purified |
|
缓 冲 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
产品描述 : |
Thyroid transcription factor 2 (TITF2; Forkhead; TH; also known as a "winged helix") . FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as monomers, are also found in the Hepatocyte nuclear factor (HNF) proteins, which provide tissue-specific gene regulation. The structure contains 2 flexible loops or "wings" in the C-terminal region, hence the term winged helix. Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. |
| 适用物种 : |
Hu, Mo, Rat, Chi, Dog, Pig, Cow |
| 应用说明 : |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
| 别 名 : |
FKH L15; FKHL 15; FKHL15; Forkhead (Drosophila) like 15; forkhead (Drosophila)-like 15; forkhead box E1; Forkhead box E2; Forkhead box protein E1; Forkhead drosophila homolog like 15; Forkhead like 15; Forkhead related protein FKHL 15; Forkhead related protein FKHL15; FOX E1; FOX E2; FOXE 1; FOXE 2; FOXE-2; FOXE1; FOXE2; HFKH 4; HFKH4; HFKL 5; HFKL5; homolog-like 15; thyroid transcription factor 2; thyroid transcription factor-2; TITF 2; TITF2; TTF 2; TTF-2; TTF2; FOXE1_HUMAN. |
| 保存条件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
| 标 记 物 : |
PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体 |
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产品说明 : |
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