| 克隆类型 : |
Rabbit Polyclonal IgG |
|
免 疫 原 : |
Peptide derived from human CCT2. |
|
纯化方式 : |
Immunogen affinity purified |
|
缓 冲 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
产品描述 : |
CCT2 is one of eight largely unrelated subunit proteins found in a protein chaperone complex known as the chaperonin-containing TCP-1 (CCT) or TRiC complex. The CCT complex is an abundanct cytoslic component that is credited with helping newly synthesized polypeptides adopt the correct conformation (1). Proteins that fold and assemble with the help of CCT include the cytoskeletal proteins actin and tubulin as well as up to 15% of newly synthesized eukaryotic proteins (2). CCT2 is the β-subunit of the chaperone complex and is one of several CCT proteins that exhibit increased expression in response to stress. This implies that the CCT complex helps cells recover from protein damage by assisting in protein folding and assembly (3). CCT subunit levels also change throughout the cell cycle, with lower proteins levels (and reduced chaperone activity) found during induced cell cycle arrest during at M phase (4). |
| 适用物种 : |
Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Zebrafish, Sheep |
| 应用说明 : |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
| 别 名 : |
CCT2;CCT beta; CCTB; Chaperonin containing t complex polypeptide 1 beta subunit; Chaperonin containing t complex polypeptide 1 subunit 2; Chaperonin containing TCP1 subunit 2; Chaperonin containing TCP1 subunit 2 (beta); CTP:phosphocholine cytidylyltransferase 2; T complex protein 1 beta subunit; T complex protein 1 subunit beta; TCP 1 beta; TCP-1-beta; TCPB_HUMAN. |
| 保存条件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
| 标 记 物 : |
PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体 |
|
产品说明 : |
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