C2CD3 Antibody_华拓生物

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C2CD3 Antibody

产品名称 ： C2CD3 Antibody

中文名称 ： C2CD3蛋白抗体

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0306884

规　　格 ： 0.1mg(1mg/ml)

详细信息

克隆类型：	Rabbit Polyclonal IgG
免疫原：	Peptide derived from human C2CD3.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	C2CD3 (C2 domain-containing protein 3), also known as FLJ34770, is a 2,353 amino acid protein that contains two C2 domains. C2 domains are regions of about 130 amino acid residues that are found in proteins that bind phospholipids. It is thought that calcium binding to the C2 domain induces an electrostatic potential change that enhances phospholipid binding, which suggests a role for the domain as an electrostatic switch. C2CD3 is expressed as five isoforms produced by alternative splicing events. The gene that encodes C2CD3 maps to human chromosome 11, which makes up around 4% of human genomic DNA. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene.
适用物种：	Hu, Mo, Rat, Dog
应用说明：	E: 1:500-1:1000 IHC: 1:200-1:1000
别　　名：	C2 domain-containing protein 3; C2CD3; C2CD3_HUMAN.
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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