克隆类型 : |
Rabbit Polyclonal IgG |
免 疫 原 : |
Peptide derived from Hu AANAT. |
纯化方式 : |
Immunogen affinity purified |
缓 冲 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
产品描述 : |
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
适用物种 : |
Hu, Mo, Rat, Dog, |
应用说明 : |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
别 名 : |
SNAT_Hu; AANAT; Arylalkylamine N acetyltransferase; Serotonin N-acetyltransferase; SNAT. |
保存条件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
标 记 物 : |
PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体 |
产品说明 : |
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