Aprataxin Antibody_华拓生物

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Aprataxin Antibody

产品名称 ： Aprataxin Antibody

中文名称 ：共济失调性眼球运动功能丧失相关蛋白AOA1抗体

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0310012

规　　格 ： 0.1mg(1mg/ml)

详细信息

克隆类型：	Rabbit Polyclonal IgG
免疫原：	peptide derived from human Aprataxin.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	Aprataxin is a nuclear protein, present in both the nucleoplasm and the nucleolus, which is a member of the histidine triad (HIT) superfamily. Aprataxin is involved in DNA single-strand break repair, mediating protein-protein interactions with molecules responding to DNA damage. Aprataxin contains three conserved domains: an N-terminal forkhead-associated (FHA) domain which mediates protein-protein interactions, a HIT domain that is similar to Hint, and a C-terminal zinc finger domain. Loss of function mutations in APTX, the gene encoding for Aprataxin, destabilize the Aprataxin protein and result in a rare neurological disorder known as ataxia-oculomotor apraxia, characterized by abnormal movements of the head and eyes.
适用物种：	Hu, Mo, Rat, Hor, Sheep
应用说明：	WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500
别　　名：	AOA; AOA1; Aprataxin; Aprataxin homolog; APTX; APTX_HUMAN; Ataxia 1 early onset with hypoalbuminemia; AXA1; EAOH; EOAHA; FHA HIT;Forkhead associated domain histidine triad like.
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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