克隆类型 : |
Rabbit Polyclonal IgG |
免 疫 原 : |
Peptide derived from Hu ABCG2. |
纯化方式 : |
Immunogen affinity purified |
缓 冲 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
产品描述 : |
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. |
适用物种 : |
Hu, Mo, Rat, |
应用说明 : |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
别 名 : |
ABC15; ABCG2; ABCG2_Hu; ABCP; ATP binding cassette sub family G (WHITE) member 2; ATP binding cassette transporter G2; ATP-binding cassette sub-family G member 2; BCRP1; BMDP; Breast cancer resistance protein; CD338; CDw338; CDw338 antigen; GOUT1; Mitoxantrone resistance associated protein; MRX; Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2; MXR; MXR1; Placenta specific ATP binding cassette transporter; Placenta specific MDR protein; UAQTL1. |
保存条件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
标 记 物 : |
PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体 |
产品说明 : |
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