克隆类型 : |
Rabbit Polyclonal IgG |
免 疫 原 : |
Peptide derived from Hu TBP Associated Factor 1. |
纯化方式 : |
Immunogen affinity purified |
缓 冲 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
产品描述 : |
Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. |
适用物种 : |
Hu, Mo, Rat, Chi, Dog, Cow, Hor, |
应用说明 : |
E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
别 名 : |
TBP Associated Factor 1; BA2R; CCG1; CCGS; Cell cycle G1 phase defect; Cell cycle gene 1 protein; Complementation of cell cycle block G1 to S; DYT3 protein; NSCL2; OF; p250; TAF 2A; TAF(II)250; TAF1; TAF1 RNA polymerase II TATA box binding protein (TBP) associated factor 250kDa; TAF1 RNA polymerase II TATA box binding protein (TBP) associated factor; TAF1_Hu. |
保存条件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
标 记 物 : |
PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体 |
产品说明 : |
|