| 克隆类型 ： |
Rabbit Polyclonal IgG |
|
免 疫 原 ： |
peptide derived from human MUSK. |
|
纯化方式 ： |
Immunogen affinity purified |
|
缓 冲 液 ： |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
产品描述 ： |
Receptor tyrosine kinases (RTKs) represent an important class of transmembrane signaling molecules. Binding of the extracellular domain of an RTK to its cognate ligand leads to receptor dimerization and the activation of the intrinsic tyrosine kinase activity of its intracellular kinase domain. The specificity of this type of cellular communication is conferred in part by the distribution of the receptor, which determines the cells that are capable of responding to a given ligand. MuSK, for muscle-specific kinase, is an RTK that is uniquely specific to the skeletal muscle lineage. MuSK is expressed at low levels in proliferating myoblasts, but is induced upon terminal differentiation and myotube fusion. In the embryo, MuSK is expressed in developing muscle, but its level of expression is dramatically reduced in mature muscle, where it is abundant only at the neuromuscular junction. |
| 适用物种 ： |
Hu, Mo, Rat, Dog, Pig, Cow |
| 应用说明 ： |
WB: 1:200-1:1000 IHC: 1:200-1:1000 IF: 1:50-1:200 |
| 别 名 ： |
skeletal receptor tyrosine-protein kinase; MDK4; Muscle; Muscle skeletal receptor tyrosine kinase; Muscle specific kinase receptor; MuSK; Neural fold somite kinase 1; Neural fold somite kinase 2; Neural fold somite kinase 3; Nsk1; Nsk2; Nsk3; Receptor tyrosine kinase MuSK; Skeletal muscle receptor tyrosine kinase; MUSK_HUMAN. |
| 保存条件 ： |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
| 标 记 物 ： |
PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体 |
|
产品说明 ： |
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