| 克隆类型 ： |
Rabbit Polyclonal IgG |
|
免 疫 原 ： |
phosphopeptide derived from human MUC1 around the phosphorylation site of Tyr1229. |
|
纯化方式 ： |
Immunogen affinity purified |
|
缓 冲 液 ： |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
产品描述 ： |
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. |
| 适用物种 ： |
Hu, Mo, Rat, Dog, Pig, Hor |
| 应用说明 ： |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
| 别 名 ： |
MUC1 (phospho Y1229); p-MUC1 (phospho Y1229); ADMCKD; ADMCKD1; Breast carcinoma associated antigen DF3; CA15 3; CA15 3 antigen; Cancer antigen 15-3; Carcinoma associated mucin; CD227; CD227 antigen; DF3 antigen; EMA; Episialin; Epithelial basement membrane antigen; Epithelial membrane antigen; Epithelial mucin tandem repeat sequence; H23 antigen; H23AG; KL6; Krebs von den Lungen-6; MAM6; MCD; MCKD; MCKD1; Medullary cystic kidney disease 1 (autosomal dominant); MUC-1/SEC; MUC-1/X; MUC1; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; MUC1_HUMAN. |
| 保存条件 ： |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
| 标 记 物 ： |
PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体 |
|
产品说明 ： |
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