| 克隆类型 : |
Rabbit Polyclonal IgG |
|
免 疫 原 : |
peptide derived from human PMCA4B. |
|
纯化方式 : |
Immunogen affinity purified |
|
缓 冲 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
产品描述 : |
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. |
| 适用物种 : |
Hu, Mo, Rat, Pig, Cow, Hor |
| 应用说明 : |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:50-1:200 |
| 别 名 : |
PMCA4x; AT2B4_HUMAN; ATP2B2; ATPase Ca++ transporting plasma membrane 4; Cation transporting ATPase; Matrix remodelling associated 1; Matrix remodelling associated protein 1; MXRA1; Plasma membrane calcium ATPase 4; Plasma membrane calcium ATPase isoform 4; PMCA4. |
| 保存条件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
| 标 记 物 : |
PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体 |
|
产品说明 : |
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