克隆类型 : |
Rabbit Polyclonal IgG |
免 疫 原 : |
PhosphoPeptide derived from Hu c-Abl isoform b around the phosphorylation site of Tyr272. |
纯化方式 : |
Immunogen affinity purified |
缓 冲 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
产品描述 : |
The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c Abl proto oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase. |
适用物种 : |
Hu, Mo, Rat, Dog, Pig, Cow, Hor |
应用说明 : |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
别 名 : |
c Abl (phospho Y272); p-c Abl (phospho Y272); Abelson Murine Leukemia Viral Oncogene Homolog 1; Abelson murine leukemia viral v abl oncogene homolog 1; ABL; Abl protein; Abl1; Bcr/c abl oncogene protein; JTK7; p150 ; Proto oncogene tyrosine protein kinase ABL1; Transformation gene oncogene ABL; v abl Abelson murine leukemia viral oncogene homolog 1; v abl. |
保存条件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
标 记 物 : |
PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体 |
产品说明 : |
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