RNF142 Antibody_华拓生物

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RNF142 Antibody

产品名称 ： RNF142 Antibody

中文名称 ：环指蛋白142抗体

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0312349

规　　格 ： 0.1mg(1mg/ml)

详细信息

克隆类型：	Rabbit Polyclonal IgG
免疫原：	peptide derived from human SH3MD2/RNF142.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network.
适用物种：	Hu, Mo, Rat, Chi, Dog, Cow, Hor
应用说明：	WB: 1:200-1:1000 IHC: 1:200-1:1000 IF: 1:50-1:200
别　　名：	Plenty of SH3 domains; Plenty of SH3s; POSH; Ring finger protein 142; RNF142; SH3 domain containing ring finger 1;SH3MD2; SH3 multiple domains 2; SH3RF1.
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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