CXCR4 Antibody_华拓生物

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CXCR4 Antibody

产品名称 ： CXCR4 Antibody

中文名称 ：细胞表面趋化因子受体4抗体

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0502512

规　　格 ： 0.1ml(100ug/200ul)

详细信息

克隆类型：	Rabbit Polyclonal IgG
免疫原：	peptide from near the N terminal residues of human CXCR4 protein.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	CXCR-4 is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. The structure of CXCR4 in complex with CXCL12 was elucidated in;[3] the computationally derived CXCL12 : CXCR4 complex structure is in remarkable agreement with experimental findings and sheds light into the functional role of CXCL12 and CXCR4 residues which are associated with binding and signaling. CXCR4 is one of several chemokine receptors that HIV can use to infect CD4+ T cells. The molecular recognition of CXCR4 is predominantly mediated through the V3 loop fragment of HIV protein gp120. A computationally derived structure of CXCR4 in complex with a dual HIV-1 gp120 V3 loop was reported in.[4] The structure is in remarkable agreement with previous experimental findings and sheds light into the role of HIV-1 and CXCR4 residues which are associated with HIV-1 coreceptor activity.
适用物种：	Hu, Mo, Rat
应用说明：	WB: 1:200-1:1000 E: 1:20000-1:80000
别　　名：	FB22, HM89, LAP3, LCR1, NPYR, WHIM, CD184,LESTR, NPY3R, NPYRL, HSY3RR, NPYY3R, D2S201E
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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