Survivin Antibody_华拓生物

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Survivin Antibody

产品名称 ： Survivin Antibody

中文名称 ：细胞凋亡抑制因子抗体

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0502529

规　　格 ： 0.1ml(100ug/200ul)

详细信息

克隆类型：	Rabbit Polyclonal IgG
免疫原：	peptide from near the C terminal residues of human Survivin protein.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	Survivin is a member of the inhibitor of apoptosis (IAP) family. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. This has been shown by disruption of survivin induction pathways leading to increase in apoptosis and decrease in tumour growth. The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells. These data suggest survivin might provide a new target for cancer therapy that would discriminate between transformed and normal cells. Survivin expression is also highly regulated by the cell cycle and is only expressed in the G2-M phase. It is known that survivin localizes to the mitotic spindle by interaction with tubulin during mitosis and may play a contributing role in regulating mitosis.
适用物种：	Hu
应用说明：	WB: 1:200-1:1000 E: 1:20000-1:80000 IHC: 1:100-1:500
别　　名：	API4, EPR-1
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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