pdk1 Antibody_华拓生物

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pdk1 Antibody

产品名称 ： pdk1 Antibody

中文名称 ：磷酸化3磷酸肌醇依赖性蛋白激酶1

产品类别 ：一抗

品　　牌 ： PLLABS

货　　号 ： PL0502578

规　　格 ： 0.1ml(100ug/200ul)

详细信息

克隆类型：	Rabbit Polyclonal IgG
免疫原：	peptide from near the C terminal residues of human pdk1 protein.
纯化方式：	Immunogen affinity purified
缓冲液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
产品描述：	The Pyruvate Dehydrogenase (PDH) complex must be tightly regulated due to its central role in general metabolism. Within the complex, there are three serine residues on the E1 component that are sites for phosphorylation; this phosphorylation inactivates the complex. In humans, there have been four isozymes of Pyruvate Dehydrogenase Kinase that have been shown to phosphorylate these three sites: PDK1, PDK2, PDK3, and PDK4. PDK1 is the only enzyme capable of phosphorylating the 3rd serine site. When the TPP coenzyme is bound, the rates of phosphorylation by all four isozymes are drastically affected; specifically, the incorporation of phosphate groups by PDK1 into sites 2 and 3 is significantly reduced.
适用物种：	Hu
应用说明：	WB: 1:200-1:1000 E: 1:20000-1:80000
别　　名：	PDPK1, PRO0461, MGC20087, MGC35290
保存条件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
标记物：	PLLABS公司可供应生物素、辣根过氧化物酶、荧光素标记抗体
产品说明：

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