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序 列 ： |
The synthetic peptide used to raise the antibody Cat. No. 250549 is selected from a sequence within the N-term region of human ABCB6. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
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纯 度 ： |
Purity > 80% by HPLC |
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形 态 ： |
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect. |
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溶 解： |
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
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保存条件 ： |
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
| 别 名 ： |
ABCB6; ATP-binding cassette sub-family B member 6, mitochondrial; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; Ubiquitously-expressed mammalian ABC half transporter; P-glycoprotein-related protein; MTABC3; PRP; UMAT |
| 产品链接 ： |
http://www.ABBIOTEC.com/peptides/abcb6-peptide |
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产品说明 ： |
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| 产品描述 ： |
ATP-binding cassette sub-family B member 6, mitochondrial (ABCB6) binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. ABCB6 plays a crucial role in heme synthesis. Depletion of ABCB6 by RNAi abrogates heme biosynthesis. Overexpression enhances porphyrin biosynthesis. |
