|
序 列 ： |
Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala or LKKFNARRKLKGAILTTMLA |
| 分 子 式 ： |
C103H185N31O24S1 |
|
分 子 量 ： |
2273.9 g/mol |
|
纯 度 ： |
Purity > 95% by HPLC |
|
形 态 ： |
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt. |
|
溶 解： |
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
|
保存条件 ： |
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C. |
| 别 名 ： |
Calcium/calmodulin-dependent protein kinase type II alpha chain; CaM-kinase II alpha chain; CaM kinase II subunit alpha; CaMK-II subunit alpha; CAMK2A; CAMKA; KIAA0968 |
| 产品链接 ： |
http://www.ABBIOTEC.com/peptides/camkii-%25255B290-309%25255D-inhibitory-peptide%2525C2%2525A0 |
|
产品说明 ： |
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| 产品描述 ： |
This peptide is a potent calmodulin antagonist and an inhibitor for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. The sequence derives from the residues 290-309 within the calmodulin-binding domain of human CaMKII alpha. CaMKII is a prominent kinase in the central nervous system that functions in long-term potentiation and neurotransmitter release. This peptide inhibits CaMKII activation by blocking calmodulin binding to CaMKII. |
