产品货号Reference:              CAN-E-7030
检测方法Kit Type:                 Competitive LIA
规格Kit Size:                         96-well break-apart microplate
灵敏度Sensitivity:                 0.03 ng/mL
检测样本Sample Type:         Human saliva / 50 μL
检测范围Calibrator Range:  0.03–30 ng/mL
检测时间Total Assay Time:  95 minutes
背景介绍：
在妊娠期间，雌三醇的测定用于监测胎儿的健康状况。因此，在怀孕期间，雌三醇水平可以检测到胎儿发育的异常。随着怀孕时间的推移，雌三醇的浓度也会增加。唾液中未结合雌三醇的含量反映了血清中未结合雌三醇的浓度，因此唾液中未结合雌三醇的测定对跟踪妊娠的进展具有重要的临床意义。唾液中的未结合雌三醇水平反映了fl的生物活性部位。
唾液的收集与尿液和血清相比有许多优点，因为它是一种非侵入性的程序，可以很容易地在家里收集和冷冻储存。
由于唾液中未结合雌三醇的浓度较低，我们建立了一种基于化学发光免疫分析(LIA)的检测系统。该方法灵敏度高(0.03 ng/mL)，准确、准确，在摇床上的RT°孵育时间为75分钟。
During pregnancy the determination of estriol is used for monitoring fetal well being. Therefore, during pregnancy the estriol level can detect abnormalities in the development of the fetus. As pregnancy progresses in time the concentration of Estriol also increases. The unconjugated estriol saliva determination is of great clinical importance to follow the progress of pregnancy since the level of salivary unconjugated estriol reflects the unconjugated estriol concentration in serum, which refl ects the biologically active fraction.
The collection of saliva has advantages compared to urine and serum since it is a non-invasive procedure which can be easily collected at home and stored frozen.
Due to the low concentration of unconjugated estriol in saliva we have developed an assay system using a chemiluminescent immunoassay (LIA). The assay is very sensitive (0.03 ng/mL), precise and accurate along with a short incubation time of 75 minutes at RT° on a shaker.

注：本产品仅用于科研用途，不能直接用于人体或临床诊断使用。