产品货号Reference:              CAN-DHT-280
检测方法Kit Type:                 Competitive ELISA
规格Kit Size:                         96-well break-apart microplate
灵敏度Sensitivity:                 6 pg/mL
检测样本Sample Type:         Human serum / 50 μL
校准范围Calibrator Range:  25–2500 pg/mL
检测时间Total Assay Time:  75 minutes

背景介绍：

5双氢睾酮(α-dihydrotone，DHT)是一种类似于睾酮和雄烯二酮的甾体，属于雄激素类。
DHT是一种C19类固醇，具有雄激素活性。雄激素的大量产生主要发生在睾丸的间质细胞中。雄激素在血液中循环与蛋白质结合，特别是性激素结合球蛋白(SHBG)和白蛋白。微量的类固醇在血液中以未结合的形式循环，被称为游离组分。DHT对SHBG的亲和力至少是睾酮的三倍。在男性中，大约70%的DHT来自外周睾酮的转化，而在女性中，大部分DHT来自雄烯二酮。
5α-dihydrotestosterone (DHT) is a steroid similar to testosterone and androstenedione, which belong to a class called androgens.
DHT is a C19 steroid and possesses androgenic activity. The bulk of androgen production takes place mainly in the Leydig cells of the testes. Androgens circulate in the blood bound to proteins, especially sex hormone binding globulin (SHBG) and albumin. A trace amount of these steroids circulate in the unbound form in the blood and are referred to as the free fractions. DHT has at least three times the binding affinity for SHBG than testosterone. In males about 70% of DHT is derived from peripheral conversion of testosterone, while in females most of the DHT is derived from androstenedione.