前列腺特异性酸性磷酸酶抗体/PSAP Antibody |
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产品名称 ： 前列腺特异性酸性磷酸酶抗体/PSAP Antibody
产品类别 ： IVD诊断抗体原料
品 牌 ： GenomeMe
货 号 ： IHC655
规 格 ： 0.1ml/1ml
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详细信息 |
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纯化方式 ：
缓 冲 液 ：
应用说明 ：
形 态 ：
产品说明 ：
背景描述Description：
前列腺特异性酸性磷酸酶(PSAP)是在前列腺腺上皮中发现的一种前列腺酶。PSAP水平在前列腺增生和前列腺癌中升高，在转移性前列腺癌中检测到的水平最高。中度过表达PSAP也是骨病(如Paget病或甲状旁腺功能亢进)、血细胞病(如镰状细胞病)、多发性骨髓瘤或溶酶体贮积性疾病(如高雪氏病)的特征。PSAP被认为比PSA更敏感，但特异性更低，然而，在适当的临床环境下，抗PSAP可以作为抗PSA的有益补充。
Prostatic Specific Acid Phosphatase (PSAP) is a prostatic enzyme found in the glandular epithelium of the prostate. PSAP levels are elevated in hyperplastic prostate and prostate carcinoma, with the highest levels being detected in metastasized prostate cancer. Moderate overexpression of PSAP is also characteristic of diseases of the bone (such as Paget’s disease or hyperparathyroidism), diseases of blood cells (such as sickle-cell disease), multiple myeloma, or lysosomal storage diseases (such as Gaucher’s disease). PSAP is considered more sensitive, yet less specific, than PSA, however Anti-PSAP can act as a useful complement to Anti-PSA under suitable clinical contexts.
Specifications：
Clone： IHC655
Source： Mouse Monoclonal
Positive Control： Prostate, Prostate Adenocarcinoma
Dilution Range： 1:50-1:200
参考文献References：
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Epstein JI. Urol Clin North Am. 1993; 20:757-70.
van Krieken JH. Am J Surg Pathol. 1993; 17:410-4.
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